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preservation of these materials and will provide the routine analysis of their constituents which, can be determined by known chemical technics such as determination of potassium, sodium and other inorganic constituents, their organiejsonstituents such as bile acids, urea, non-protein nitrogen, C02 combining power, etc. The other biochemist will be engaged in specialized analysis, such as electrophoresis, spectrographic analysis, etc. and will try to devise new methods for the determination of teste amines, phenols, etc. Bio-Assay of Body Fluids. Another laboratory will be maintained in the animal house for bio-assay on laboratory animals aaf the toxic constituents isolated in the chemical laboratory. Animal Experimentation. "While the chief interest in the toxic cerebral state centers in patients, it is planned nevertheless, to produce these conditions in laboratory animals and to carry out parallel studies on their body fluids. Both, uremia and hepatic coma are readily produced in laboratory animals, such as dogs, rabbits, guinea pigs and rats by the surgical removal of the kidneys or liver, or through selective poisoning of these organs. A highly specific form of chemical damage to the liver can be achieved by injecting carbon tetrachloride into the portal vein and a highly selective form of renal damage can be produced by injecting HgClg into the renal arteries. Laboratory animals also offer the best available means for the analysis of the cerebral effects of neurotoxic chemical compounds. f^NSmjjppITmGENCE SOURCE'S inv/m vm