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e FD-302a (Rev. 10-6-95) 279A-WF-222936-BREI Continuation of FD-302 of | | ,On 01/18/2008 Page 2 was shown the sequence "TTTAATTAT", which [] initially associated with the sequence for a TATA box. SEARLS explained that a TATA box is a promoter region in DNA that serves as a binding site for transcription regulators. From his computer [______Jprinted the Wikipedia description for the box, and Position-specific scoring matrix, which is mathematical representation of conformity to known patterns in biological sequences. [_____Jreassessed the "TTTAATTAT" sequence to be less likely a TATA box sequence. agreed that the DNA sequence could also be translated to an amino acid sequence, yielding three (3) results, depending on the reading frame. The first sequence frame codes for "Phenylalanine - Asparagine - Tyrosine", the second sequence frame codes for "Leucine - Isoleucine", and the third sequence frame codes for "STOP codon - Leucine". [__Jexpressea that, translation of the "TTTAATTAT" sequence to amino acids, is how a person who works with proteins would view the sequence. All the paperwork shown to, and provided by L___Jare included in the 1A, along with the original interview notes, business card, Curriculum Vitae, and an e-mail with