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ii, The intensive repetition (16 hours a day *1 ^ for 6 or 7 days) of the prearranged verbal signal. iii. During this period of intensive repetition the patient is kept in partial sensory isolation. iv. Repression of the driving period is carried out by putting the patient, after the conclusion of the period, into continuous sleep for 7-10 days, In .! .Mil'll! I>. In brffig'alro^^f^ioI^Fal^chalige by the repetition of appropriate verba?, signals. We have used the same technique as is outlined above for the production of behavioral change. We have been successful in achieving change in physiological function with respect to: • (a) the balance of flexor and extensor muscles in the arm; (b) the relationship of the blood pressure levels in the right and left arms. j/p 3, Specific Propos als Vie now propose to carry on further studies upon the effects of ore determined signals upon: (a) physio- logical functions; (b) patterns of behavior. To further this, wo have two major, immediate objectives: i. To improve the technique of heteropsychic driving (the repetition of predetermined verbal signals of our own devising). ii. To investigate the range of physiological functions vrtiich can be changed by these procedures. Fir st Objective : Among the studies which we propose to carry out in pursuit of our first objective are:- (a) Can we find chemical agents which will serve to break down the ongoing patterns of behavior: more rapidly more transitorily with less damage to the perceptive and cognitive capacities of the individual than the present physiological agents.